Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Taiwan ODM expert factory for comfort product development
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Pillow OEM for wellness brands Indonesia
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Soft-touch pillow OEM manufacturing factory in Taiwan
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Phage illustration. Tailocins look like phages, but don’t have the capsid (“head”) that contains the viral DNA and replication machinery. A Berkeley Lab-led team is digging into the bizarre bacteria-produced nanomachines that could fast-track microbiome science. Imagine there are arrows that are lethal when fired on your enemies yet harmless if they fall on your friends. It’s easy to see how these would be an amazing advantage in warfare, if they were real. However, something just like these arrows does indeed exist, and they are used in warfare … just on a different scale. These weapons are called tailocins, and the reality is almost stranger than fiction. “Tailocins are extremely strong protein nanomachines made by bacteria,” explained Vivek Mutalik, a research scientist at Lawrence Berkeley National Laboratory (Berkeley Lab) who studies tailocins and phages, the bacteria-infecting viruses that tailocins appear to be remnants of. “They look like phages but they don’t have the capsid, which is the ‘head’ of the phage that contains the viral DNA and replication machinery. So, they’re like a spring-powered needle that goes and sits on the target cell, then appears to poke all the way through the cell membrane making a hole to the cytoplasm, so the cell loses its ions and contents and collapses.” An illustration of tailocins, and their altruistic action painted by author Vivek Mutalik’s daughter, Antara. Credit: Antara Mutalik A wide variety of bacteria are capable of producing tailocins, and seem to do so under stress conditions. Because the tailocins are only lethal to specific strains — so specific, in fact, that they have earned the nickname “bacterial homing missiles” — tailocins appear to be a tool used by bacteria to compete with their rivals. Due to their similarity with phages, scientists believe that the tailocins are produced by DNA that was originally inserted into bacterial genomes during viral infections (viruses give their hosts instructions to make more of themselves), and over evolutionary time, the bacteria discarded the parts of the phage DNA that weren’t beneficial but kept the parts that could be co-opted for their own benefit. But, unlike most abilities that are selected through evolution, tailocins do not save the individual. According to Mutalik, bacteria are killed if they produce tailocins, just as they would be if they were infected by a true phage virus, because the pointed nanomachines erupt through the membrane to exit the producing cell much like replicated viral particles. But once released, the tailocins only target certain strains, sparing the other cells of the host lineage. “They benefit kin but the individual is sacrificed, which is a type of altruistic behavior. But we don’t yet understand how this phenomenon happens in nature,” said Mutalik. Scientists also don’t know precisely how the stabbing needle plunger of the tailocin functions. These topics, and tailocins as a whole, are an area of hot research due to the many possible applications. Mutalik and his colleagues in Berkeley Lab’s Biosciences Area along with collaborators at UC Berkeley are interested in harnessing tailocins to better study microbiomes. Other groups are keen to use tailocins as an alternative to traditional antibiotics -which indiscriminately wipe out beneficial strains alongside the bad and are increasingly ineffective due to the evolution of drug-resistance traits. In their most recent paper, the collaborative Berkeley team explored the genetic basis and physical mechanisms governing how tailocins attack specific strains, and looked at genetic similarities and differences between tailocin producers and their target strains. After examining 12 strains of soil bacteria known to use tailocins, the biologists found evidence that differences in the lipopolysaccharides — fat- and sugar-based molecules — attached to the outer membranes could determine whether or not a strain is targeted by a particular tailocin. “The bacteria we studied live in a challenging, resource-poor environment, so we’re interested to see how they might be using tailocins to fight for survival,” said Adam Arkin, co-lead author and a senior faculty scientist in the Biosciences Area and technical co-manager of the Ecosystems and Networks Integrated with Genes and Molecular Assemblies (ENIGMA) Scientific Focus Area. Arkin noted that although scientists can easily induce bacteria to produce tailocins in the lab (and can easily insert the genes into culturable strains for mass production, which will be handy if we want to make tailocins into medicines) there are still a lot of unanswered questions about how bacteria deploy tailocins in their natural environment, as well as how — and why — particular strains are targeted with an assassin’s precision. “Once we understand the targeting mechanisms, we can start using these tailocins ourselves,” Arkin added. “The potential for medicine is obviously huge, but it would also be incredible for the kind of science we do, which is studying how environmental microbes interact and the roles of these interactions in important ecological processes, like carbon sequestration and nitrogen processing.” Currently, it’s very difficult to figure out what each microbe in a community is doing, as scientists can’t easily add and subtract strains and observe the outcome. With properly harnessed tailocins, these experiments could be done easily. Mutalik, Arkin, and their colleagues are also conducting follow-up studies aiming to reveal tailocins’ mechanisms of action. They plan to use the advanced imaging facilities at Berkeley Lab to take atomic-level snapshots of the entire process, from the moment the tailocin binds to the target cell all the way to cell deflation. Essentially, they’ll be filming frames of a microscopic slasher movie. Reference: “Systematic discovery of pseudomonad genetic factors involved in sensitivity to tailocins” by Sean Carim, Ashley L. Azadeh, Alexey E. Kazakov, Morgan N. Price, Peter J. Walian, Lauren M. Lui, Torben N. Nielsen, Romy Chakraborty, Adam M. Deutschbauer, Vivek K. Mutalik and Adam P. Arkin, 1 March 2021, The ISME Journal. DOI: 10.1038/s41396-021-00921-1 This work is part of the ENIGMA Scientific Focus Area, a multi-institutional consortium led by Berkeley Lab focused on advancing our understanding of microbial biology and the impact of microbial communities on their ecosystems. ENIGMA is supported by the Department of Energy’s Office of Science.
A new study published in Scientific Reports revealed that dogs understand the relationship between their body and the environment in a problem solving task. The researchers of the Department of Ethology at Eötvös Loránd University (Budapest, Hungary) found that dogs can recognize their body as an obstacle, which ability is one of the basic manifestations of self-representation in humans. Self-Representation in Animals May Develop in Different Forms Depending on Ecological Needs. A new study published in Scientific Reports revealed that dogs understand the relationship between their body and the environment in a problem solving task. The researchers of the Department of Ethology at Eötvös Loránd University (Budapest, Hungary) found that dogs can recognize their body as an obstacle, which ability is one of the basic manifestations of self-representation in humans. Self-representation is the ability to hold information in one’s own mental model about themselves. In humans, this capacity reaches an extremely complex form, called self-consciousness. However, some of its elements might appeared during the evolution of non-human animals, too, according to the given species’ ecological needs. “Dogs are perfect subjects for the investigation of the self-representation related abilities as we share our anthropogenic physical and social environment with them. Thus, it is reasonable to assume that at least some of its forms might appeared in them, too. From these, body-awareness might be one of the most basic ones” — explains Rita Lenkei, PhD student, first author of the study. The researchers adapted a paradigm that was previously used only in elephants and humans. During the original test the toddlers are requested to hand over a blanket or mat they are sitting on. However, this task can only be executed if the subjects understand the connection between their own body and the mat, consequently, firstly they have to leave the mat before passing it to the experimenter. In the case of dogs, the method had to be modified to the four-legged subjects, and a ball was attached to the mat so dogs immediately understood the request of the owner to pass the object (together with the mat). “We developed a more complex method than the original one to make sure that dogs only leave the mat when it was truly necessary. Based on our results even during their first attempt they left the mat significantly sooner and more likely when it was needed to solve the task, compared to when, for instance, the ball was anchored to the ground” — says Dr. Péter Pongrácz, principal investigator. Insights into Animal Cognition and Evolution The results are particularly interesting in light of the fact that this experiment is believed to be related to the well-known mirror mark experiment, in which both humans and elephants perform well. Moreover, in toddlers the onset of succeeding in this test appears at the same time — regardless of the age of the subject — when the recognition of the self-reflection in the mirror. “Based on our knowledge the dog is the first species that did not pass the mirror mark test but successfully passed the ‘body as an obstacle’ paradigm. Our results support the theory about self-representation as being an array of more or less connected cognitive skills, where the presence or lack of a particular building block may depend on the ecological needs and cognitive complexity of the given species” — points out Lenkei. Reference: “Dogs (Canis familiaris) recognize their own body as a physical obstacle” by Rita Lenkei, Tamás Faragó, Borbála Zsilák and Péter Pongrácz, 18 February 2021, Scientific Reports. DOI: 10.1038/s41598-021-82309-x
MIT biological engineers have devised a way to perform large-scale screens of how T cells such as this one recognize specific pathogens, such as the HIV viruses (yellow) show in this image. Credit: Seth Pincus, Elizabeth Fischer and Austin Athman, National Institute of Allergy and Infectious Diseases/NIH MIT biological engineers have developed a simple way to identify B or T cells that interact with viral or bacterial proteins. The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells’ ability to recognize harmful microbes is critical to successfully fighting off infection. MIT biological engineers have now devised an experimental tool that allows them to precisely pick out interactions between a particular immune cell and its target antigen. The new technique, which uses engineered viruses to present many different antigens to huge populations of immune cells, could allow large-scale screens of such interactions. “This technique leads the way to understand immunity much closer to how the immune system itself actually works, will help researchers make sense of complex immune recognition in a variety of diseases, and could accelerate the development of more effective vaccines and immunotherapies,” says Michael Birnbaum, an associate professor of biological engineering at MIT, a member of MIT’s Koch Institute for Integrative Cancer Research, and the senior author of the study. Former MIT graduate student Connor Dobson is the lead author of the paper, which was published on April 8th, 2022, in Nature Methods. A Simple Screen for a Complex System Both B and T cells play critical roles in launching an immune response. When a T cell encounters its target, it starts proliferating to produce an army of identical cells that can attack infected cells. And B cells that encounter their target begin producing antibodies that help recruit other components of the immune system to clear the infection. Scientists who study the immune system have several tools to help them identify specific antigen-immune cell interactions. However, these tools generally only allow for the study of a large pool of antigens exposed to one B or T cell, or a large pool of immune cells encountering a small number of antigens. “In your body, you have millions of unique T cells, and they could recognize billions of possible antigens. All of the tools that have been developed to this point are really designed to look at one side of that diversity at a time,” Birnbaum says. The MIT team set out to design a new tool that would let them screen huge libraries of both antigens and immune cells at the same time, allowing them to pick out any specific interactions within the vast realm of possibilities. To create a simple way to screen so many possible interactions, the researchers engineered a specialized form of a lentivirus, a type of virus that scientists often use to deliver genes because it can integrate pieces of DNA into host cells. These viruses have an envelope protein called VSV-G that can bind to receptors on the surface of many types of human cells, including immune cells, and infect them. For this study, the researchers modified the VSV-G protein so that it cannot infect a cell on its own, instead relying on an antigen of the researchers’ choosing. This modified version of VSV-G can only help the lentivirus get into a cell if the paired antigen binds to a human B or T-cell receptor that recognizes the antigen. Once the virus enters, it integrates itself into the host cell’s genome. Therefore, by sequencing the genome of all the cells in the sample, the researchers can discover both the antigen expressed by the virus that infected the cell and the sequence of the T or B-cell receptor that allowed it to enter. “In this way, we can use viral infection itself as a way to match up and then identify antigen-immune cell parings,” Birnbaum says. Interactions Identified To demonstrate the accuracy of their technique, the researchers created a pool of viruses with antigens from 100 different viruses, including influenza, cytomegalovirus, and Epstein-Barr virus. They screened these viruses against about 400,000 T cells and showed that the technique could correctly pick out antigen-T-cell receptor pairings that had been previously identified. The researchers also screened two different B-cell receptors against 43 antigens, including antigens from HIV and the spike protein of SARS-CoV-2. In future studies, Birnbaum hopes to screen thousands of antigens against B and T cell populations. “Our ideal would be to screen entire viruses or families of viruses, to be able to get a readout of your entire immune system in one experiment,” he says. In one study that is now ongoing, Birnbaum’s lab is working with researchers at the Ragon Institute of MGH, MIT, and Harvard to study how different people’s immune systems respond to viruses such as HIV and SARS-CoV-2. Such studies could help to reveal why some people naturally fight off certain viruses better than others, and potentially lead to the development of more effective vaccines. The researchers envision that this technology could also have other uses. Birnbaum’s lab is now working on adapting the same viruses to deliver engineered genes to target cells. In that case, the viruses would carry not only a targeting molecule but also a novel gene that would be incorporated exclusively into cells that have the right target. This could offer a way to selectively deliver genes that promote cell death into cancer cells, for example. “We built this tool to look for antigens, but there’s nothing particularly special about antigens,” Birnbaum says. “You could potentially use it to go into specific cells in order to do gene modifications for cell and gene therapy.” The research was funded by the Koch Institute Frontier Award program, the Packard Foundation, the Damon Runyon Cancer Research Foundation, the Michelson Medical Research Foundation, Pfizer, Inc., the Department of Defense, the National Institutes of Health, a National Science Foundation Graduate Research Fellowship, a Siebel Scholarship, a Canadian Institutes of Health Research Doctoral Foreign Study Award, a graduate fellowship from the Ludwig Center at MIT, a Medical Scientist Training Program grant from the National Institute of General Medical Sciences, a Technology Impact Award from the Cancer Research Institute, the Pew-Stewart Scholarship program, and the Koch Institute Support (core) Grant from the National Cancer Institute. Reference: “Antigen identification and high-throughput interaction mapping by reprogramming viral entry” by Connor S. Dobson, Anna N. Reich, Stephanie Gaglione, Blake E. Smith, Ellen J. Kim, Jiayi Dong, Larance Ronsard, Vintus Okonkwo, Daniel Lingwood, Michael Dougan, Stephanie K. Dougan, and Michael E. Birnbaum, 8 April 2022, Nature Methods. DOI: 10.1038/s41592-022-01436-z
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