Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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High-performance graphene insole OEM China
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Graphene-infused pillow ODM Thailand
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Vietnam pillow OEM manufacturer
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China insole ODM design and production
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.ODM pillow for sleep brands Thailand
A picture of the tropical kelp forest. Credit: Charles Darwin Foundation/University of Malaga The Charles Darwin Foundation-led research holds importance due to the discovery of a new species of this type of alga, previously mostly found in colder waters. María Altamirano, a researcher from the University of Malaga’s Department of Botany and Plant Physiology, is part of the scientific team collaborating on the Charles Darwin Foundation (CDF)-led Seamounts Project. The project has uncovered a vast kelp forest on the top of a seamount at a depth of approximately 50 meters in the southern Galapagos Islands. The significance of the research, published in Marine Biology, lies in the discovery of a new species of kelp in the region and possibly in science. Conducted in collaboration with the Galapagos National Park Directorate and National Geographic, this research has characterized the ecology of this new ecosystem. Refuges for Diversity Kelps are brown algal seaweeds, famous for reaching very large sizes, which form marine forests in high densities. Similar to coral reefs and mangroves, these forests are very important for the maintenance of marine biodiversity, as they provide protection and food for many species. As kelps are cold-water species, most of these forests are found exclusively in warm-cold or polar regions and shallow coastal areas because they need constant light. However, this kelp forest of the Galapagos Marine Reserve is located in a tropical region away from coastal areas. The significance of this research, led by the Charles Darwin Foundation, lies in a new species record of this type of alga that, until now, it has been mostly found in colder waters. Credit: Charles Darwin Foundation/University of Malaga “This is the first time that such an extensive and dense kelp forest has been registered in this part of the Galapagos and at such depths, since what we found looks very different from the Eisenia galapagensis kelp species, discovered in this area in 1934”, explains Salomé Buglass, CDF scientist and lead researcher, who adds that it is almost twice the normal size. Remotely Operated Vehicles As standard scuba diving is restricted to depths of 40 meters, CDF’s research teams relied on new technologies, such as remotely operated vehicles (ROVs), to explore, document, and characterize these deep-sea ecosystems. In fact, thanks to the installation of a mechanical claw to the ROV, in 2018 Professor María Altamirano, who was in the archipelago as coordinator of a collaboration project of the University of Malaga, together with the researcher at the University of Granada Julio de la Rosa, were able to analyze specimens of this newly registered alga, “which is essential to determine its taxonomy and is still under study”. As standard scuba diving is restricted to depths of 40 meters, CDF’s research teams relied on new technologies, such as remotely operated vehicles (ROVs), to explore, document and characterize these deep-sea ecosystems. Credit: Charles Darwin Foundation/University of Malaga Explore and Protect “Despite their enormous importance as ecosystem engineers and as support for the fascinating marine life of the Galapagos Islands, the macroalgae of this area have been widely ignored among the marine ecosystems of the archipelago”, says Altamirano. “This discovery offers the opportunity to highlight its significance as habitat for other species and their role in carbon sequestration within deep-sea areas”. The scientists conclude that knowing that there are entire marine forests teeming with life that we were unaware of at only 50 m depth, serves as a reminder of how much remains to be explored, discovered, learned, and protected. Reference: “Novel mesophotic kelp forests in the Galápagos archipelago” by Salome Buglass, Hiroshi Kawai, Takeaki Hanyuda, Euan Harvey, Simon Donner, Julio De la Rosa, Inti Keith, Jorge Rafael Bermúdez and María Altamirano, 23 November 2022, Marine Biology. DOI: 10.1007/s00227-022-04142-8
Computer simulation of filaments assembling into a division ring in the middle of the cell. Credit: Nicola de Mitri New research reveals how bacterial proteins self-organize by destruction, aiding synthetic material design. How does matter, lifeless by definition, self-organize and make us alive? One of the hallmarks of life, self-organization, is the spontaneous formation and breakdown of biological active matter. However, while molecules constantly fall in and out of life, one may ask how they ‘know’ where, when, and how to assemble, and when to stop and fall apart. A team of researchers led by Professor Anđela Šarić and PhD student Christian Vanhille Campos at the Institute of Science and Technology Austria (ISTA) have addressed these questions in the context of bacterial cell division. Computational simulation of FtsZ treadmilling shows the death of misaligned filaments. Credit: © Christian Vanhille Campos, Šarić lab, ISTA Unveiling New Mechanisms of Protein Assembly The researchers developed a computational model for the assembly of a protein called FtsZ, an example of active matter. During cell division, FtsZ self-assembles into a ring structure at the center of the dividing bacterial cell. This FtsZ ring–called the bacterial division ring–was shown to help form a new ‘wall’ that separates the daughter cells. However, essential physical aspects of FtsZ self-assembly remain unknown. Computational simulation and atomic force microscopy (AFM) experiment on in vitro assemblies. Credit: © Christian Vanhille Campos, Šarić lab, including an AFM video by Philipp Radler, Loose lab, ISTA In a new study, recently published in Nature Physics, computational modelers from the Šarić group team up with experimentalists from Séamus Holden’s group at The University of Warwick, UK, and Martin Loose’s group at ISTA to reveal an unexpected self-assembly mechanism. Their computational work demonstrates how misaligned FtsZ filaments react when they hit an obstacle. By ‘dying’ and re-assembling, they favor the formation of the bacterial division ring, a well-aligned filamentous structure. These findings could have applications in the development of synthetic self-healing materials. Simulating FtsZ filament self-organization by treadmilling. Modeling the treadmilling of FtsZ filaments in a bacterial cell shows how the bacterial division ring forms. Credit: Claudia Flandoli The Role of Treadmilling in Cellular Structures FtsZ forms protein filaments that self-assemble by growing and shrinking in a continuous turnover. This process, called ‘treadmilling,’ is the constant addition and removal of subunits at opposite filament ends. Several proteins have been shown to treadmill in multiple life forms – such as bacteria, animals, or plants. Scientists have previously thought of treadmilling as a form of self-propulsion and modeled it as filaments that move forward. However, such models fail to capture the constant turnover of subunits and overestimate the forces generated by the filaments’ assembly. Computational simulation and live cell imaging in the bacterium Bacillus subtilis. Credit: © Christian Vanhille Campos, Šarić lab, ISTA, including live cell images by Kevin D. Whitley, Holden lab Thus, Šarić and her team set out to model how FtsZ subunits interact and spontaneously form filaments by treadmilling. “Everything in our cells is in a constant turnover. Thus, we need to start thinking of biological active matter from the prism of molecular turnover and in a way that adapts to the outside environment,” says Šarić. What they found was striking. In contrast to self-propelled assemblies that push the surrounding molecules and create a ‘bump’ felt at long molecular distances, they saw that misaligned FtsZ filaments started ‘dying’ when they hit an obstacle. “Active matter made up of mortal filaments does not take misalignment lightly. When a filament grows and collides with obstacles, it dissolves and dies,” says first author Vanhille Campos. Šarić adds, “Our model demonstrates that treadmilling assemblies lead to local healing of the active material. When misaligned filaments die, they contribute to a better overall assembly.” By incorporating the cell geometry and filament curvature into their model, they showed how the death of misaligned FtsZ filaments helped form the bacterial division ring. Proteins (blue) add onto a filament after binding an energy source (black) inside a cell. Credit: Nicola de Mitri Collaborative Breakthroughs in Experimental Validation Driven by the physical theories of molecular interactions, Šarić and her team soon made two independent encounters with experimental groups that helped confirm their results. At a diverse and multidisciplinary conference called ‘Physics Meets Biology,’ they met Séamus Holden, who worked on imaging bacterial ring formation in live cells. At this meeting, Holden presented exciting experimental data showing that the death and birth of FtsZ filaments were essential for the formation of the division ring. This suggested that treadmilling had a crucial role in this process. “Satisfyingly, we found that FtsZ rings in our simulations behaved in the same way as the Bacillus subtilis division rings that Holden’s team imaged,” says Vanhille Campos. Computer simulation of a division ring assembling by dissolution of misaligned model filaments. Credit: Nicola de Mitri In a similar strike of luck, relocating from University College London to ISTA allowed Šarić and her group to team up with Martin Loose, who had been working on assembling FtsZ filaments in a controlled experimental setup in vitro. They saw that the in vitro results closely matched the simulations and further confirmed the team’s computational results. Underlining the cooperation spirit and synergy between the three groups, Šarić says, “We are all stepping outside our usual research fields and going beyond what we normally do. We openly discuss and share data, views, and knowledge, which allows us to answer questions we cannot tackle separately.” Implications for Synthetic Self-Healing Materials Energy-driven self-organization of matter is a fundamental process in physics. The team led by Šarić now suggests that FtsZ filaments are a different type of active matter that invests energy in turnover rather than motility. “In my group, we ask how to create living matter from non-living material that looks living. Thus, our present work could facilitate the creation of synthetic self-healing materials or synthetic cells,” says Šarić. As a next step, Šarić and her team seek to model how the bacterial division ring helps build a wall that will divide the cell into two. Holden and Šarić will continue to investigate this question with the help of a recent 3.7 million Euro grant awarded by the Wellcome Trust. Reference: “Self-organization of mortal filaments and its role in bacterial division ring formation” by Christian Vanhille-Campos, Kevin D. Whitley, Philipp Radler, Martin Loose, Séamus Holden and Anđela Šarić, 12 August 2024, Nature Physics. DOI: 10.1038/s41567-024-02597-8
A multi-institution research team, including Cornell University, used a new suite of computational genetic tools to examine how Neanderthal genes still actively influence human traits in people of non-African ancestry, revealing that certain Neanderthal genes significantly impact modern human immune systems and other traits. Analyzing nearly 300,000 UK Biobank datasets, they found 4,303 Neanderthal genetic variants affecting 47 distinct genetic traits, with modern human genes overall winning out over generations. Neanderthal DNA persists in traits like immunity, with modern genes gradually overtaking its influence through generations. Recent scientific findings have revealed that Neanderthal DNA makes up between 1 and 4% of the genome in contemporary humans descended from ancestors who left Africa. However, it was unclear to what extent these genes continue to shape human traits – until now. A multi-institution research team including Cornell University has developed a new suite of computational genetic tools to address the genetic effects of interbreeding between humans of non-African ancestry and Neanderthals that took place some 50,000 years ago. (The study applies only to descendants of those who migrated from Africa before Neanderthals died out, and in particular, those of European ancestry.) In a study published in eLife, the researchers reported that some Neanderthal genes are responsible for certain traits in modern humans, including several with a significant influence on the immune system. Overall, however, the study shows that modern human genes are winning out over successive generations. Modern Human Genes Prevailing Over Generations “Interestingly, we found that several of the identified genes involved in modern human immune, metabolic, and developmental systems might have influenced human evolution after the ancestors’ migration out of Africa,” said study co-lead author April (Xinzhu) Wei, an assistant professor of computational biology in the College of Arts and Sciences. “We have made our custom software available for free download and use by anyone interested in further research.” Using a vast dataset from the UK Biobank consisting of genetic and trait information of nearly 300,000 Brits of non-African ancestry, the researchers analyzed more than 235,000 genetic variants likely to have originated from Neanderthals. They found that 4,303 of those differences in DNA are playing a substantial role in modern humans and influencing 47 distinct genetic traits, such as how fast someone can burn calories or a person’s natural immune resistance to certain diseases. Unlike previous studies that could not fully exclude genes from modern human variants, the new study leveraged more precise statistical methods to focus on the variants attributable to Neanderthal genes. While the study used a dataset of almost exclusively white individuals living in the United Kingdom, the new computational methods developed by the team could offer a path forward in gleaning evolutionary insights from other large databases to delve deeper into archaic humans’ genetic influences on modern humans. “For scientists studying human evolution interested in understanding how interbreeding with archaic humans tens of thousands of years ago still shapes the biology of many present-day humans, this study can fill in some of those blanks,” said senior investigator Sriram Sankararaman, an associate professor at the University of California, Los Angeles. “More broadly, our findings can also provide new insights for evolutionary biologists looking at how the echoes of these types of events may have both beneficial and detrimental consequences.” Reference: “The lingering effects of Neanderthal introgression on human complex traits” by Xinzhu Wei, Christopher R Robles, Ali Pazokitoroudi, Andrea Ganna, Alexander Gusev, Arun Durvasula, Steven Gazal, Po-Ru Loh, David Reich and Sriram Sankararaman, 20 March 2023, eLife. DOI: 10.7554/eLife.80757 The research was supported by grants from the National Institutes of Health and the National Science Foundation, with additional funding from an Alfred P Sloan Research Fellowship and a gift from the Okawa Foundation. Other authors received funding support from the Paul G. Allen Frontiers Group, the John Templeton Foundation, the Howard Hughes Medical Institute, the Burroughs Wellcome Fund, and the Next Generation Fund at the Broad Institute of MIT and Harvard.
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